Bioaxis Chemicals Co., Ltd
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NISIN

NATURAL FOOD ANTISEPTICS
TITER:≥1000IU/MG

NISIN is a polypeptide which is made by Lactococcus lactis. It is a natural, nonpoisonous and effective food antiseptic. Nisin possesses anti-microbial activity against a wide range of Gram-positive bacteria,particularly those that produce spores. It inhibits certain strains of the food pathogen,such as Clostridium botulinum, Staphylococcus aureus, Streptococcus hemolyticus, Listeria monocytogenes, Bacillus stearothermophilus, Bacillus subtilis and some others.
Nisin is used as a food preservative in a number of thermal processed foods, particularly in dairy products, canned foods, plant protein foods and cured meat etc.

BACTERIOSTASIS
The antimicrobial spectrum of Nisin shows that it can kill or inhibit G+ which can make foods putrefactive, especially to bacterial spore which has tolerance to pasteurization. Nisin can inhibit some bacteria, such as Clostridium botulinum, Bacillus cereus, Bacillus alcalophilus, and Listeria monocytogenes and so on. It is useful in 10-50ppm.

SECURITY
Nisin is a polypeptide. It will be broken down into amino acid by protease in the digestive system by being eaten. Also, it won’t change the normal bacterial community in intestine or cause drug resistance of using other antibiotic substance. Moreover, it doesn’t appear chiasmatic resistance with other antibiotic substance. The study of microbes toxicity of Nisin shows that it owns high security for having no toxicity or pathogenicity.

PACKING
500g/bottle, or according to customers’ requirement.

DOSAGE
Widely used in canned foods, meat products, dairy products, phytoprotein products and sealed packing foods with high temperature sterilization treatment.
OPERATING METHOD:
Make about 5% aqueous solutions with boiled water, and then add it to foods and mix fully (or use with other antiseptics).
The maximum dose of use is 200 mg/kg in canned foods and plant protein foods
The maximum dose of use is 500 mg/kg in dairy products and meats
General dose is 100 to 200 mg/kg

STORE
Be laid in dry, shady and cool place with sealed packing.

TECHNICAL DATA SHEET
NISIN